Treatment of Current (Active) Disease Therapy

V. Treatment of Current (Active) Disease Therapy

Last Updated April 2026

List of Subchapters

List of charts

Table 7. Recommended Regimens for Treatment of Adults and Children with Drug-Susceptible TB (Pulmonary TB)
Table 8. First-line TB Drugs: Dosing for Adults (ages 16 and over) Directly Observed Therapy (DOT) is mandatory
Table 9. Pediatric Dosage in Children (Birth to 15 Years)
Table 10. Antituberculosis Antibiotics in Adult Patients with Renal Impairment
Table 11. Antituberculosis Medications for Patients who have Contraindications to or Intolerance of First Line Agents or require IV Therapy during Acute or Critical Illness
Table 12. Clinical Situations for which Standard Therapy cannot be given or is not well-tolerated or may not be effective: Potential Alternative Regimens (Dosing and/or Drugs)
Table 13. When to Start HIV Therapy
Table 14. What to start: Choice of TB Therapy and Antiretroviral Therapy (ART) when treating Co-infected Patients
Table 15. Summary of Recommendations for Treatment of Active TB Disease in Persons with HIV
Table 16. Guidelines for Treatment of Extrapulmonary Tuberculosis: Length of Therapy and Adjunctive Use of Corticosteroids
Table 17. Use of Anti-TB Medications in Special Situations: Pregnancy, Tuberculosis Meningitis, and Renal Impairment
Table 18. Grady Hospital TB Isolation Policy

List of Figures

Figure 1. Factors to be considered in deciding to initiate treatment empirically for active tuberculosis (TB) (prior to microbiologic confirmation)