VII. Childhood Tuberculosis
Last Updated April 2026
The basic principles for treatment of TB disease and infection in children and adolescents are similar to adults. The objective of treatment is to kill the tuberculous bacilli in the shortest amount of time while preventing the development of resistance. Dosage adjustments of medications may often be required based on weight. When possible, crushed tablets or the mixed contents of capsules are preferred over suspensions that may be difficult to access and may contain fewer desirable additives.
Either TST or immunologic-based testing (IGRAs) may be used to aid in LTBI or TB disease diagnosis in immune competent children of any age. The involvement of a provider with expertise in management of children with tuberculosis infection or disease is beneficial in guiding diagnostic evaluation and treatment.